Objective?To study the application effect of Jiedu Huoxue Jianpifang on patients with colorectal adenoma polyp after operation. Methods?A total of 86 middle-aged and old patients with adenomatous polyps in the colon who received diagnosis and treatment in Shenzhen Bao 'an District Traditional Chinese Medicine Hospital from August 2019 to February 2020 were selected, all patients underwent endoscopic mucosal resection, according to random number table method they were divided into control group (43 patients, give nutrition support, anti-infection) and the observation group (43 patients, on the basis of the control group, using Jieduhuoxuejianpifang for treatment), patients in both groups were treated for 2 months, the clinical efficacy of the two groups of patients after postoperation, TCM syndrome score, serum interleukin-18 (IL-18), interleukin-17 (IL-17), interleukinIL-1β (IL-1β) levels preoperative and 2 months postoperative and recurrence 6 months after postoperation. Results?The total effective rate of observation group was higher than the control group; Compared with preoperation, the scores of abdominal pain, poor appetite, fatigue, loose stools, burning anus, tenesmus and the serum levels of IL-18, IL-17 and IL-1β of the two groups 2 months after operation decreased, and the observation group was lower than the control group; After 6 months postoperation, the recurrence rate of observation group was lower than the control group (all P